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KMID : 0978920120130040196
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Korean Journal of Clinical Geriatrics
2012 Volume.13 No. 4 p.196 ~ p.202
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Differences of Behavioural and Psychological Symptoms between Large-Vessel and Small-Vessel Vascular Dementia
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Kim Meyung-Kug
Yoo Bong-Goo
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Abstract
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Background: Behavioral and psychological symptoms of dementia (BPSD) are common manifestations of dementing disorders. Some studies have sought to identify specific BPSD that distinguish Alzheimer’s dementia from vascular dementia. We investigated the differences of BPSD between large-vessel vascular dementia and small-vessel vascular dementia.
Methods: The BPSD of 77 patients with vascular dementia determined using the Korean version of the neuropsychiatric inventory (K-NPI). The patients were classified as having large-vessel vascular dementia or small-vessel vascular dementia based on MRI.
Results: The BPSD were reported in 73% of the patients with vascular dementia. Apathy/indifference was the symptom that was reported most often in both large-vessel vascular dementia and small-vessel vascular dementia groups, followed by depression/dysphonia and anxiety. Patients with small-vessel vascular dementia reported more and severe agitation/aggression than patients with large-vessel vascular dementia (P=0.017).
Conclusion: The BPSD are frequent in vascular dementia. Patients with large-vessel vascular dementia and small-vessel vascular dementia reveal different BPSD profiles, especially more agitation/aggression in small-vessel vascular dementia.
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KEYWORD
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Behavioral and psychological symptoms of dementia, Vascular dementia, Apathy, Agitation
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